Job Description


Contract Duration: months

Purpose:

We are building comprehensive Model-Informed Drug Development (MIDD) capabilities in-house to create reusable platform models across our oncology portfolio. We seek a talented and motivated expert to develop advanced Quantitative Systems Pharmacology (QSP) models in oncology that enable Virtual Population simulations. You will act as a MIDD expert for oncology and integrate this knowledge into Clinical Pharmacology strategy for related development programs.

This means:

  • Develop QSP platform models for multiple oncology mechanisms including: Immune checkpoint inhibitors (IO/ICI) across colorectal, lung, and ovarian cancers Antibody-drug conjugates across lung, ovarian, and colorectal cancers T-cell engagers and bispecifics/trispecifics in multiple myeloma CAR-T therapies in hematologic malignancies
  • Create and optimize Virtual Populations to capture patient heterogeneity and support clinical...
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