Postdoctoral Associate in Computational Multi-Omics for Immunotherapy

Overview

The Morrissy Lab is seeking a highly motivated scientist with expertise in bioinformatics and data science to join as a Postdoctoral Associate focused on understanding immunotherapy responses in solid tumors. The candidate will use state-of-the-art analytic approaches to investigate multi-omics data and derive an in-depth understanding of tumor ecosystem dynamics in clinical samples from immunotherapy trials – including phenotypic and functional cell heterogeneity, tumor and microenvironment cell niches, and cellular crosstalk. This research is primarily focused on cohorts of single-patient and phase I clinical trial participants treated with CAR T-cells, and identifying mechanisms of immunotherapy response and resistance from longitudinally-collected blood and tumor tissue samples. The candidate will employ innovative bioinformatics and machine learning approaches to integrate single cell and spatial datasets from clinical samples with data from ongoing preclin...