Job Description
A PhD position is available in the lab Structure and Function of Membrane Proteins” at the VIB-VUB Center for Structural Biology in Brussels, Belgium. The project focuses on the structural elucidation of membrane protein complexes and integrates fundamental cell biology and structural biology by cryo- electron microscopy.
The lab has a strong track record in investigating scramblases and their role in membrane remodeling. It also aims to deepen the mechanistic understanding of solute transport in ion channels and transporters of medical relevance.
We apply state of the art methods for the purification of fragile membrane protein complexes, either from cultured mammalian cells or from native sources. These complexes are studied through tailored biochemical, biophysical, and cell biological assays, including liposome preparations and confocal microscopy. For structural work, single particle cryo-electron microscopy is extensively utilized at the Biological Electron Cryogenic Micros...
The lab has a strong track record in investigating scramblases and their role in membrane remodeling. It also aims to deepen the mechanistic understanding of solute transport in ion channels and transporters of medical relevance.
We apply state of the art methods for the purification of fragile membrane protein complexes, either from cultured mammalian cells or from native sources. These complexes are studied through tailored biochemical, biophysical, and cell biological assays, including liposome preparations and confocal microscopy. For structural work, single particle cryo-electron microscopy is extensively utilized at the Biological Electron Cryogenic Micros...
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