Job Description

Are you excited about exploring the biology behind phages infecting dormant bacteria? Join forces to uncover fundamental biology with great potential for clinical impact.
We offer a fully funded PhD position on how phages kill dormant bacteria.

Your function

Scientific background: If you take a bus, you probably want the driver to be awake. Similarly, bacteriophages (viruses that infect bacteria) have long been assumed to require metabolically active hosts. However, several recent studies and our own findings challenge this assumption. We have identified over a dozen phages capable of replicating in growth-arrested E. coli, suggesting that dormancy-killing is far more common than previously recognized. How do phages replicate in dormant cells? The phages we discovered are genetically diverse and differentially respond to bacterial knock-outs, pointing to multiple, evolutionarily distinct solutions to this challenge. 

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