Job Description

Essential Duties and responsibilities

  • Responsible for the design, analysis, interpretation, and reporting of preclinical, clinical DMPK and clinical pharmacology data generated at external vendors and academic sites
  • Serve as a primary source of scientific expertise for the design, analysis, reporting and presentation of pharmacokinetic and pharmacodynamic modeling and simulation data
  • Provide DMPK guidance for hit to lead and lead optimization in discovery programs.
  • Support tox studies by guiding BA method development and validation as well as TK analysis.
  • Prepare strategic and scientifically sophisticated DMPK and clinical pharmacology drug development strategies that meet regulatory requirements and program goals
  • Participate in the management of CROs and academic sites in the conduct of in vitro/in vivo ADME, DMPK and clinical pharmacology studies
  • Design and oversee clinical food effects, drug-drug interac...

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